Why Zebras? The PI community often identifies with zebras. This is based on an old saying. In medical school, many doctors learn the saying, “when you hear hoof beats, think horses, not zebras” and are taught to focus on the likeliest possibilities when making a diagnosis, not the unusual ones. However, sometimes physicians need to look for a zebra. People with PI are the zebras of the medical world. So IDF says THINK ZEBRA!
"Dr. Ogden Bruton was a pediatrician at Walter Reed Army Hospital in the early 1950s when he first saw a young boy presenting with recurrent lung infections. Testing revealed that the boy had no circulating antibodies in the blood, making it difficult for his body to fight infection. The boy’s disease became known as X-linked a-gammaglobulin anemia – or Bruton’s Agammaglobulinemia – and its identification was heralded as an important medical discovery, even being featured as such by TIME magazine in 1953."
"X-Linked Agammaglobulinemia (XLA) was first described in 1952 by Dr. Ogden Bruton. This disease, sometimes called Bruton’s Agammaglobulinemia or Congenital Agammaglobulinemia, was one of the first immunodeficiency diseases to be identified. XLA is an inherited immunodeficiency disease in which patients lack the ability to produce antibodies, the proteins that make up the gamma globulin or immunoglobulin fraction of blood plasma."